Editorial Type: REVIEW
 | 
Online Publication Date: 12 Sept 2025

Muscling Up on Mental Illness: A Review on Physical Activity in Mental Health Care

MSc, ESSAM AEP,
PhD, ESSAM AEP,
PhD, ESSAM AEP,
PhD, ESSAM AEP,
ESSAM AEP,
S.Ft., Physio, MSc, and
PhD, ESSAM AEP
Article Category: Review Article
Page Range: 85 – 93
DOI: 10.31189/CEPH-25-00002
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ABSTRACT

Mental illnesses encompass a broad spectrum of disorders, each presenting unique challenges and psychosocial impacts that can affect individuals’ daily lives and overall well-being to varying degrees. While treatments are available, a large treatment gap exists between those requiring mental health care and those who access mental health care. Pharmacotherapy and psychotherapy are often first-line treatments; however, when accessible, barriers to adherence exist, including medication side effects and long appointment waitlists. International guidelines increasingly recommend physical activity due to significant mental and physical health benefits for people experiencing mental illness. These recommendations are founded on well-established evidence supporting the use of physical activity interventions in both the prevention and treatment of several mental illnesses including depressive disorders, anxiety and stress-related disorders, schizophrenia spectrum disorders, and bipolar disorders. Clinical exercise professionals are well placed to deliver physical activity interventions to people living with mental illnesses. To do so effectively, they must remain informed about the recent research and understand the unique considerations to working in mental health settings. In this brief review, we aim at summarizing high-level evidence regarding physical activity and mental health prevention and treatment from meta-analyses, meta-reviews, systematic reviews, umbrella reviews, expert guidelines, and clinical treatment guidelines. We also recommend strategies for clinical exercise professionals to increase intervention engagement and discuss the evidence for preventing physical comorbidities in people with mental illness.

Copyright: Copyright © 2025 Clinical Exercise Physiology Association 2025
FIGURE 1.
FIGURE 1.

Summary of evidence for physical activity and depressive disorders.


FIGURE 2.
FIGURE 2.

Summary of evidence for physical activity and anxiety and stress-related disorders.


FIGURE 3.
FIGURE 3.

Summary of evidence for physical activity and schizophrenia spectrum disorders.


FIGURE 4.
FIGURE 4.

Summary of evidence for physical activity and bipolar disorders.


Contributor Notes

Address for correspondence: Chiara Mastrogiovanni. MSc, Discipline of Psychiatry and Mental Health, School of Clinical Medicine, University of New South Wales Kensington, NSW 2052, Australia; +61 451 652 163; e-mail: c.mastrogiovanni@unsw.edu.au

Conflicts of Interest and Source of Funding: The authors declare no conflicts of interest. This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors. CM is supported by the UNSW Research Training Program (RTP) Scholarship. SR is funded by an NHMRC EL2 fellowship (APP2017506).

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